In present study, the methanol extracts and all fractions of leaves of Bauhinia acuminata were subjected to various biological screening such as membrane stabilizing activity and antimicrobial screening. This investigation suggested that, leaves of Bauhinia acuminata were highly effective in the membrane stabilizing activity as the extractives prevented the lysis of erythrocyte by hypotonic solution and heat induced. In hypotonic solution induced condition the highest membrane stabilizing activity was exhibited by the Pet ether soluble fraction (PESF-418.26%) followed by carbon tetra chlororide soluble fraction (CTCSF-418.26%). Significant amount of membrane stabilizing activity were also present in methanol soluble fraction (MESF-13.46%) and aqueous soluble fraction (AQSF-167.30%). On the other hand, heat induced condition the maximum membrane stabilizing activity was exhibited by the carbon tetra chlororide soluble fraction (CTCSF-853.3%) followed by Methanol soluble fraction (MESF-423.88%). Significant amount of membrane stabilizing activity were also present in Pet ether soluble fraction (PESF-81.77%) and aqueous soluble fraction (AQSF-40.46%). In this study, the antimicrobial activity, among all extractives of leaves of Bauhinia acuminate was found to be negligible.
| Published in | American Journal of Life Sciences (Volume 2, Issue 5) |
| DOI | 10.11648/j.ajls.20140205.13 |
| Page(s) | 267-270 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Bauhinia Acuminate, Anti-Inflammatory, Antimicrobial Activity
| [1] | Verdcourt, B. 1979. A Manual of New Guinea Legumes. Office of Forests division of botany, Lae (Papua New Guinea). 645pp. |
| [2] | Howard, Richard A. 1988. Flora of the Lesser Antilles: Leeward and Windward Islands. Vol. 4, Dicotyledoneae-Part 1. Arnold Arboretum, Harvard University. 673 pp. |
| [3] | Sadipa nag, Anirban Paul, Ritu Parna Datta. Phytochemical analysis of methanolic extract of some medicinal plants. International Journals of scientific and research publications 2013; 3(4) p1648. |
| [4] | Van Wagenen, B.C., Larsen, R., Cardellina, J.H., Ran dazzo, D., Lidert, Z.C. and Swithenbank, C. 1993. Ulosantoin, a potent insecticide from the sponge Ulosa ruetzleri. J. Org. Chem. 58, 335-337. |
| [5] | Mounnissamy VM, Kavimani S, Balu V, Drlin QS: Evaluation of anti-inflammatory and membrane stabilizing properties of ethanol extract of Canjera rehedi. Iranian Journal of Pharmacology and Therapeutics 2008, 6:235-237. |
| [6] | Shinde UA, Phadke AS, Nair AM, Mungantiwar AA, Dikshit VJ and Saraf MN: Preliminary studies on the immunomodulatory activity of Cedrus deodara wood oil. Fitoterapia 1999; 70: 333-339. |
| [7] | Sikder MA, Rahman MA, Kaisar MA, Rahman MS, Hasan CM and Rashid MA: In vitro Antioxidant, reducing power, free radical scavenging and membrane stabilizing activities of seeds of Syzygium cumini L. Latin American Journal of Pharmacy 2011; 30: 781-5. |
| [8] | Reyad-ul-Ferdous M, Azam MG and Hossain MD: Phytochemical screening, in-vitro membrane stabilizing and thrombolytic activities of Lophopetalum javanicum. Int J Pharm Sci Res 2014; 5(2): 350-53. |
| [9] | Bauer AW, Kirbey WMM, Sherries JC, Truck M. Antibiotic susceptibility testing by standardized single disc method. Am J Clinical Pathol 1996; 45: 493- 496. |
| [10] | Chaitanya R, Sandhya S, David B, Vinod KR, Murali S: HRBC Membrane Stabilizing Property of Roor, Stem and Leaf of Glochidion velutinum. International Journal of Research in Pharmaceutical and Biomedical sciences 2011; 2(1):256-259. |
| [11] | Middleton E, Kandaswami C: Effect of flavonoids on immune and inflammatory cell function. Biochemical Pharmacology 1992; 43:1167-1179. |
| [12] | Read MA: Flavonoids: naturally occurring anti-inflammatory agents. American Journal of Pathology 1995; 147:235-237. |
| [13] | Oweyele B, Oloriegbe YY, Balaogun EA, Soladoye AO: Analgesis and anti-inflammatory properties of Nelsonia Canescens leaf extract. Journal of Ethnopharmacology 2005; 99:153-156. |
| [14] | Md. Reyad-ul-Ferdous, Mosharaf Hossen and Fazle Noor Biswas. In-vitro potential antimicrobial and antioxidant activities of Lablab niger leaves. International Journal of Pharma Sciences and Research 2014; 5(6): 257-261. |
APA Style
Md. Reyad-Ul-Ferdous, Sayma Akhter, Md. Zahirul Islam Khan, Md. Eshak Khan, Md. Atiqul Islam, et al. (2014). Ex-Vivo Anti-Inflammatory and Antimicrobial Activities of the Leaves of Bauhinia acuminata. American Journal of Life Sciences, 2(5), 267-270. https://doi.org/10.11648/j.ajls.20140205.13
ACS Style
Md. Reyad-Ul-Ferdous; Sayma Akhter; Md. Zahirul Islam Khan; Md. Eshak Khan; Md. Atiqul Islam, et al. Ex-Vivo Anti-Inflammatory and Antimicrobial Activities of the Leaves of Bauhinia acuminata. Am. J. Life Sci. 2014, 2(5), 267-270. doi: 10.11648/j.ajls.20140205.13
AMA Style
Md. Reyad-Ul-Ferdous, Sayma Akhter, Md. Zahirul Islam Khan, Md. Eshak Khan, Md. Atiqul Islam, et al. Ex-Vivo Anti-Inflammatory and Antimicrobial Activities of the Leaves of Bauhinia acuminata. Am J Life Sci. 2014;2(5):267-270. doi: 10.11648/j.ajls.20140205.13
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ajls.20140205.13,
author = {Md. Reyad-Ul-Ferdous and Sayma Akhter and Md. Zahirul Islam Khan and Md. Eshak Khan and Md. Atiqul Islam and Md. Sharif Ullah},
title = {Ex-Vivo Anti-Inflammatory and Antimicrobial Activities of the Leaves of Bauhinia acuminata},
journal = {American Journal of Life Sciences},
volume = {2},
number = {5},
pages = {267-270},
doi = {10.11648/j.ajls.20140205.13},
url = {https://doi.org/10.11648/j.ajls.20140205.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20140205.13},
abstract = {In present study, the methanol extracts and all fractions of leaves of Bauhinia acuminata were subjected to various biological screening such as membrane stabilizing activity and antimicrobial screening. This investigation suggested that, leaves of Bauhinia acuminata were highly effective in the membrane stabilizing activity as the extractives prevented the lysis of erythrocyte by hypotonic solution and heat induced. In hypotonic solution induced condition the highest membrane stabilizing activity was exhibited by the Pet ether soluble fraction (PESF-418.26%) followed by carbon tetra chlororide soluble fraction (CTCSF-418.26%). Significant amount of membrane stabilizing activity were also present in methanol soluble fraction (MESF-13.46%) and aqueous soluble fraction (AQSF-167.30%). On the other hand, heat induced condition the maximum membrane stabilizing activity was exhibited by the carbon tetra chlororide soluble fraction (CTCSF-853.3%) followed by Methanol soluble fraction (MESF-423.88%). Significant amount of membrane stabilizing activity were also present in Pet ether soluble fraction (PESF-81.77%) and aqueous soluble fraction (AQSF-40.46%). In this study, the antimicrobial activity, among all extractives of leaves of Bauhinia acuminate was found to be negligible.},
year = {2014}
}
TY - JOUR T1 - Ex-Vivo Anti-Inflammatory and Antimicrobial Activities of the Leaves of Bauhinia acuminata AU - Md. Reyad-Ul-Ferdous AU - Sayma Akhter AU - Md. Zahirul Islam Khan AU - Md. Eshak Khan AU - Md. Atiqul Islam AU - Md. Sharif Ullah Y1 - 2014/10/20 PY - 2014 N1 - https://doi.org/10.11648/j.ajls.20140205.13 DO - 10.11648/j.ajls.20140205.13 T2 - American Journal of Life Sciences JF - American Journal of Life Sciences JO - American Journal of Life Sciences SP - 267 EP - 270 PB - Science Publishing Group SN - 2328-5737 UR - https://doi.org/10.11648/j.ajls.20140205.13 AB - In present study, the methanol extracts and all fractions of leaves of Bauhinia acuminata were subjected to various biological screening such as membrane stabilizing activity and antimicrobial screening. This investigation suggested that, leaves of Bauhinia acuminata were highly effective in the membrane stabilizing activity as the extractives prevented the lysis of erythrocyte by hypotonic solution and heat induced. In hypotonic solution induced condition the highest membrane stabilizing activity was exhibited by the Pet ether soluble fraction (PESF-418.26%) followed by carbon tetra chlororide soluble fraction (CTCSF-418.26%). Significant amount of membrane stabilizing activity were also present in methanol soluble fraction (MESF-13.46%) and aqueous soluble fraction (AQSF-167.30%). On the other hand, heat induced condition the maximum membrane stabilizing activity was exhibited by the carbon tetra chlororide soluble fraction (CTCSF-853.3%) followed by Methanol soluble fraction (MESF-423.88%). Significant amount of membrane stabilizing activity were also present in Pet ether soluble fraction (PESF-81.77%) and aqueous soluble fraction (AQSF-40.46%). In this study, the antimicrobial activity, among all extractives of leaves of Bauhinia acuminate was found to be negligible. VL - 2 IS - 5 ER -
Email: