The pathophysiology of pain in multiple sclerosis (MS) is poorly understood, but there are multiple schools of thought. Different mechanisms are associated with causation of this pain e.g. acute pain due to inflammation; chronic or intermittent neuropathic pain related to central nervous system (CNS) lesions; pain secondary to spasticity, spasms and muscle cramps from higher motor neuron lesions; and musculoskeletal pain from adopting maladaptive body positions and general physical deconditioning. Similarly evidence for treating pain in MS is limited. Treatment is often based on anecdotal reports and clinical experience as there is scarcity of randomized placebo-controlled trials for evidence of pharmacological treatment of pain in MS. The aim of this article is to provide a brief review of current concepts about the nature, causes and management of pain in MS.
| Published in | American Journal of Internal Medicine (Volume 2, Issue 2) |
| DOI | 10.11648/j.ajim.20140202.13 |
| Page(s) | 20-25 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Multiple Sclerosis, Chronic Pain, Neuropathic Pain
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APA Style
A. R. M. Saifuddin Ekram, Ng Louisa, Bhasker Amatya, Fary Khan. (2014). Chronic Pain in Multiple Sclerosis: An Overview. American Journal of Internal Medicine, 2(2), 20-25. https://doi.org/10.11648/j.ajim.20140202.13
ACS Style
A. R. M. Saifuddin Ekram; Ng Louisa; Bhasker Amatya; Fary Khan. Chronic Pain in Multiple Sclerosis: An Overview. Am. J. Intern. Med. 2014, 2(2), 20-25. doi: 10.11648/j.ajim.20140202.13
AMA Style
A. R. M. Saifuddin Ekram, Ng Louisa, Bhasker Amatya, Fary Khan. Chronic Pain in Multiple Sclerosis: An Overview. Am J Intern Med. 2014;2(2):20-25. doi: 10.11648/j.ajim.20140202.13
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Download@article{10.11648/j.ajim.20140202.13,
author = {A. R. M. Saifuddin Ekram and Ng Louisa and Bhasker Amatya and Fary Khan},
title = {Chronic Pain in Multiple Sclerosis: An Overview},
journal = {American Journal of Internal Medicine},
volume = {2},
number = {2},
pages = {20-25},
doi = {10.11648/j.ajim.20140202.13},
url = {https://doi.org/10.11648/j.ajim.20140202.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20140202.13},
abstract = {The pathophysiology of pain in multiple sclerosis (MS) is poorly understood, but there are multiple schools of thought. Different mechanisms are associated with causation of this pain e.g. acute pain due to inflammation; chronic or intermittent neuropathic pain related to central nervous system (CNS) lesions; pain secondary to spasticity, spasms and muscle cramps from higher motor neuron lesions; and musculoskeletal pain from adopting maladaptive body positions and general physical deconditioning. Similarly evidence for treating pain in MS is limited. Treatment is often based on anecdotal reports and clinical experience as there is scarcity of randomized placebo-controlled trials for evidence of pharmacological treatment of pain in MS. The aim of this article is to provide a brief review of current concepts about the nature, causes and management of pain in MS.},
year = {2014}
}
TY - JOUR T1 - Chronic Pain in Multiple Sclerosis: An Overview AU - A. R. M. Saifuddin Ekram AU - Ng Louisa AU - Bhasker Amatya AU - Fary Khan Y1 - 2014/03/20 PY - 2014 N1 - https://doi.org/10.11648/j.ajim.20140202.13 DO - 10.11648/j.ajim.20140202.13 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 20 EP - 25 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20140202.13 AB - The pathophysiology of pain in multiple sclerosis (MS) is poorly understood, but there are multiple schools of thought. Different mechanisms are associated with causation of this pain e.g. acute pain due to inflammation; chronic or intermittent neuropathic pain related to central nervous system (CNS) lesions; pain secondary to spasticity, spasms and muscle cramps from higher motor neuron lesions; and musculoskeletal pain from adopting maladaptive body positions and general physical deconditioning. Similarly evidence for treating pain in MS is limited. Treatment is often based on anecdotal reports and clinical experience as there is scarcity of randomized placebo-controlled trials for evidence of pharmacological treatment of pain in MS. The aim of this article is to provide a brief review of current concepts about the nature, causes and management of pain in MS. VL - 2 IS - 2 ER -
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